Adhesion of Staphylococcus aureus bacteria to the epithelium cells of the pharnyx in clinical tests while applying placebo and Medistus® Antivirus.
There was an in vitro test taking place to study the effect of Medistus® Antivirus on the adhesion of Staphylococcus aureus bacteria to the bronchial epithelial cells. The aim of the test was to investigate whether Medistus® Antivirus interferes with the adhesion of bacteria to cells and thus capable to prevent or to reduce the infection. For this purpose, one cell layer (BEAS-2B human bronchial epithelium) treated with the solution of Medistus® Antivirus lozenges and another one without treatment was incubated with an initial germ count (2,7×106 CFU / ml – 3,7×106 CFU / ml) bacteria for 1 hour. After the incubation and the rinsing of the non-adherent germs, the germ count on the cells which had already been infected was determined by lysis of the bronchial epithelium cells.
Result: On the cell layer treated with Medistus® Antivirus solution, the bacterial adhesion decreased by 75% compared to the untreated cell layer.
IN VITRO STUDIES
The antiviral effect of Medistus® Antivirus lozenges against the common seasonal flu (H1N1) was successfully tested in an accredited, highly recognized German laboratory (1). The test was carried out according to DIN EN 14476, both at low (clean conditions) and at OECD high protein concentration (heavy load condition) (2). In both cases the test delivered a clear and convincing result: in the solution of Medistus® Antivirus lozenge H1N1 viruses got inactivated in just 15 seconds. Medistus® Antivirus proved exceptionally effective against the common flu virus.
After the very successful test against common flu, Medistus® Antivirus lozenges were put to a more severe test: because of its strong protein coat extremely resistant and therefore very dangerous Asian influenza virus type H2N2 (avian flu) was incubated with the solution of Medistus® Antivirus lozenges. The test delivered even under difficult conditions remarkable results: in clean conditions Medistus® Antivirus could inactivate the virus in 5 minutes. When applying a heavy load protein mix according to OECD guidelines, Medistus® lozenges could reduce the virus count by 3 log units in only 10 minutes. Against this background, the assumption is entirely justified that even the tenacious avian flu virus gets completely inactivated by Medistus® Antivirus in real life conditions.
The test results clearly indicate the powerful effect of Medistus® Antivirus lozenges in inactivating influenza viruses.
(1) BioTeSys GmbH: In-vitro Studie zur Untersuchung des Effekts von Lutschpastillen auf die Viruslast. BTS 1114/2017. Datum: 13.11.2017. Esslingen/Germany